CSIR – National Institute for Interdisciplinary Science and Technology (NIIST)

Council of Scientific & Industrial Research (CSIR), Govt.Of India Thiruvananthapuram.

Research Highlights

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    Vitamin C: Sources, Functions, Sensing and Analysis

    Sudha J. Devaki and Reshma Lali Raveendran

    Vitamin C is a water-soluble compound found in living organisms. It is an essential nutrient
    for various metabolism in our body and also serves as a reagent for the preparation of many materials in the pharmaceutical and food industry. In this perspective, this chapter can develop interest and curiosity among [...]

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    PEDOT- Reduced Graphene oxide- Silver Hybrid Nanocomposite Modified Transducer for the Detection of Serotonin

    Neethu Kalloor Sadanandhan. Molji Cheriyathuchenaaramvalli, Sudha J Devaki*
    A. R. Ravindranatha Menon

    We have developed PEDOT – reduced graphene oxide – silver hybrid nanocomposite (PEDOTNTs/rGO/Ag NPs) modified electrode as a transducer for the detection of serotonin. Structure and properties of the nanocomposites were characterized by XPS, XRD, SEM, TEM, FT-IR, UV–Visible, and Raman spectroscopy. The electrochemical impedance [...]

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    Design of Macroscopically Ordered Liquid Crystalline Hydrogel Columns Knitted with Nanosilver for Topical Applications

    Reshma Lali Raveendran, Nishanth Kumar Sasidharan, and Sudha J. Devaki*
    The design of liquid crystalline hydrogels knitted with silver nanoparticles in macroscopic ordering is becoming a subject of research interest due to their promising multifunctional applications in biomedical and optoelectronic applications. The present work describes the development of liquid crystalline Schiff-based hydrogel decorated with silver nanoparticles [...]

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    Self- Assembled Polyaniline Nanowires Stippled Graphene- 3 – Pentadecylphenyl Phosphate Hybrid Nanocomposite Based Green Sustainable Electrodes for Supercapacitors

    C. Molji, A. Aashish, K. S. Neethu and Sudha J. Devaki*
    Self-assembled polyaniline nanowires stippled graphene nanocomposites (PGPCs) were prepared by in situ polymerisation of aniline in the presence of 3-pentadecylphenyl phosphate (3-PDPP) modified graphene sheets. 3-PDPP is an amphiphilic dopant derived from cardanol obtained as a waste byproduct from the cashew industry, [...]

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    Selective degradation of the recalcitrant cell wall of Scenedesmus quadricauda CASA CC202

    Ragini Reshma1,2 and Muthu Arumugam1,2*
    Microalgae are the source for many nutritionally important bioactive compounds and potential drugs.. Even though edible microalgae are rich in nutraceutical, bioavailability of all these molecules is very less due to their rigid recalcitrant cell wall. For example, the cell wall of Scenedesmus quadricauda CASA CC202 is made up of [...]

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    Emergence of Gold- Mesoporous Silica Hybrid Nanotheranostics : Dox – Encoded, Folate Targeted Chemotherapy with Modulation of SERS Fingerprinting for Apoptosis Toward Tumor Eradication

    Adukkadan N. Ramya, Manu M. Joseph,* Santhi Maniganda, Varsha Karunakaran, Sreelekha T. T.,* and Kaustabh Kumar Maiti*
    Strategically fabricated theranostic nanocarrier delivery system is an unmet need in personalized medicine. Herein, this study reports a versatile folate receptor (FR) targeted nanoenvelop delivery system (TNEDS) fabricated with gold core silica shell followed by chitosan–folic acid conjugate surface [...]

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    EXPLORATION OF BIOGENIC NANO CHEMOBIOTICS FABRICATED BY SILVER NANOPARTICLE AND GALACTOXYLOGLUCAN WITH AN EFFICIENT BIODISTRIBUTIONIN SOLID TUMOR INVESTIGATED BY SERS FINGERPRINTING

    Manu M. Joseph,Jyothi B. Nair,Ramya N. Adukkadan,NeethuHari,Raveendran K. Pillai,Ananthakrishnan J. Nair,Kaustabh Kumar Maiti,*and Sreelekha Therakathinal T*
    An incredible exploration ensued of a dual modality nanocomposite whereinchemotherapy in fusion with antibacterial efficacy is obtained in a biogenic fabrication, which transformed as a novel nano-chemobiotics (NCB) prevailing fundamental molecular level investigation by surface-enhanced Raman scattering (SERS) platform. The [...]

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    SINGLE CELL LIPID PROFILING OF SCENEDESMUS QUADRICAUDA CASA-CC202 UNDER NITROGEN STARVED CONDITION BY SURFACE ENHANCED RAMAN SCATTERING (SERS) FINGERPRINTING

    A.N. Ramya, P.S. Ambily, B.S. Sujitha, MuthuArumugam*, Kaustabh Kumar Maiti*
    Oleaginous microalgae tend to accumulate neutral lipids as their energy reserve mainly in the form of triacylglycerol (TAG) which can be utilized as the precursor molecule for biodiesel and other nutraceuticalapplication. The TAG level and the fatty acid composition of microalgae modulated by exposing the algal [...]

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    A RATIOMETRIC NEAR INFRARED FLUOROGEN FOR THE REAL TIME VISUALIZATION OF INTRACELLULAR REDOX STATUS DURING APOPTOSIS

    GiridharanSaranya, PalapuravanAnees, Manu M. Joseph, Kaustabh K. Maiti,* and Ayyappanpillai Ajayaghosh*
    Direct monitoring of apoptotic progression is a major step forward for the early assessment of therapeutic efficacy of certain treatments and the accurate evaluation of the spread of a disease. Here, the regulatory role of glutathione (GSH) is explored as a potential biomarker for [...]

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    Antibacterial and anti tubercular evaluation of dihydronaphthalenone-indole hybrid analogues

    Praveen Kumar. V, Renjitha. J, Fathimath Salfeena. C.T, Ashitha. K.T, Sunil Varughese,
    B. S. Sasidhar*

    A new series of indole appended dihydronaphthalenone hybrid analogues have been synthesized through the Lewis acid catalyzed Michael addition of indoles to the arylidene/hetero arylidene ketones. All the synthesized derivatives are well characterized through the 1H-NMR, 13C-NMR, HRMS spectroscopic techniques and further [...]

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