CSIR – National Institute for Interdisciplinary Science and Technology (NIIST)

Council of Scientific & Industrial Research (CSIR), Govt.Of India Thiruvananthapuram.

Research Highlights

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    Self- Assembled Polyaniline Nanowires Stippled Graphene- 3 – Pentadecylphenyl Phosphate Hybrid Nanocomposite Based Green Sustainable Electrodes for Supercapacitors

    C. Molji, A. Aashish, K. S. Neethu and Sudha J. Devaki*
    Self-assembled polyaniline nanowires stippled graphene nanocomposites (PGPCs) were prepared by in situ polymerisation of aniline in the presence of 3-pentadecylphenyl phosphate (3-PDPP) modified graphene sheets. 3-PDPP is an amphiphilic dopant derived from cardanol obtained as a waste byproduct from the cashew industry, [...]

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    Selective degradation of the recalcitrant cell wall of Scenedesmus quadricauda CASA CC202

    Ragini Reshma1,2 and Muthu Arumugam1,2*
    Microalgae are the source for many nutritionally important bioactive compounds and potential drugs.. Even though edible microalgae are rich in nutraceutical, bioavailability of all these molecules is very less due to their rigid recalcitrant cell wall. For example, the cell wall of Scenedesmus quadricauda CASA CC202 is made up of [...]

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    Emergence of Gold- Mesoporous Silica Hybrid Nanotheranostics : Dox – Encoded, Folate Targeted Chemotherapy with Modulation of SERS Fingerprinting for Apoptosis Toward Tumor Eradication

    Adukkadan N. Ramya, Manu M. Joseph,* Santhi Maniganda, Varsha Karunakaran, Sreelekha T. T.,* and Kaustabh Kumar Maiti*
    Strategically fabricated theranostic nanocarrier delivery system is an unmet need in personalized medicine. Herein, this study reports a versatile folate receptor (FR) targeted nanoenvelop delivery system (TNEDS) fabricated with gold core silica shell followed by chitosan–folic acid conjugate surface [...]

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    EXPLORATION OF BIOGENIC NANO CHEMOBIOTICS FABRICATED BY SILVER NANOPARTICLE AND GALACTOXYLOGLUCAN WITH AN EFFICIENT BIODISTRIBUTIONIN SOLID TUMOR INVESTIGATED BY SERS FINGERPRINTING

    Manu M. Joseph,Jyothi B. Nair,Ramya N. Adukkadan,NeethuHari,Raveendran K. Pillai,Ananthakrishnan J. Nair,Kaustabh Kumar Maiti,*and Sreelekha Therakathinal T*
    An incredible exploration ensued of a dual modality nanocomposite whereinchemotherapy in fusion with antibacterial efficacy is obtained in a biogenic fabrication, which transformed as a novel nano-chemobiotics (NCB) prevailing fundamental molecular level investigation by surface-enhanced Raman scattering (SERS) platform. The [...]

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    SINGLE CELL LIPID PROFILING OF SCENEDESMUS QUADRICAUDA CASA-CC202 UNDER NITROGEN STARVED CONDITION BY SURFACE ENHANCED RAMAN SCATTERING (SERS) FINGERPRINTING

    A.N. Ramya, P.S. Ambily, B.S. Sujitha, MuthuArumugam*, Kaustabh Kumar Maiti*
    Oleaginous microalgae tend to accumulate neutral lipids as their energy reserve mainly in the form of triacylglycerol (TAG) which can be utilized as the precursor molecule for biodiesel and other nutraceuticalapplication. The TAG level and the fatty acid composition of microalgae modulated by exposing the algal [...]

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    A RATIOMETRIC NEAR INFRARED FLUOROGEN FOR THE REAL TIME VISUALIZATION OF INTRACELLULAR REDOX STATUS DURING APOPTOSIS

    GiridharanSaranya, PalapuravanAnees, Manu M. Joseph, Kaustabh K. Maiti,* and Ayyappanpillai Ajayaghosh*
    Direct monitoring of apoptotic progression is a major step forward for the early assessment of therapeutic efficacy of certain treatments and the accurate evaluation of the spread of a disease. Here, the regulatory role of glutathione (GSH) is explored as a potential biomarker for [...]

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    Antibacterial and anti tubercular evaluation of dihydronaphthalenone-indole hybrid analogues

    Praveen Kumar. V, Renjitha. J, Fathimath Salfeena. C.T, Ashitha. K.T, Sunil Varughese,
    B. S. Sasidhar*

    A new series of indole appended dihydronaphthalenone hybrid analogues have been synthesized through the Lewis acid catalyzed Michael addition of indoles to the arylidene/hetero arylidene ketones. All the synthesized derivatives are well characterized through the 1H-NMR, 13C-NMR, HRMS spectroscopic techniques and further [...]

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    Acrylamide formation in plantain (Musa paradisiaca) chips influenced by different ripening stages: A correlation study with respect to reducing sugars, amino acids and phenolic content

    L. Shamla, P. Nisha
    The effect of ripening on the formation of acrylamide in deep fried plantain chips made from Nendran variety (Musa paradisiaca) was investigated. The precursors of acrylamide formation, reducing sugars (glucose and fructose) and ten major amino acids, were quantified during different stages of ripening using HPLC and correlated with acrylamide formation. The [...]

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    Green Solid Ionic Liquid Crystalline Electrolyte Membranes with Anisotropic Channels for Efficient Li-Ion Batteries

    Renjith Sasi, Bongu Chandrasekhar, Nallathamby Kalaiselvi*, and Sudha J. Devaki*

    Adv. Sustainable Syst. 2017, 1600031
    A biobased ionic liquid crystal derived solid polymer electrolyte (BILC-SPE) membrane, consisting of polymeric backbone, lithium salt, and cardanol derived ionic liquid crystals along with conventional plasticizer is fabricated using a facile and simple strategy. The in-house prepared solid polymer electrolyte membrane [...]

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    Novel organomodified kaolin/silica hybrid fillers in natural rubber and its blend with polybutadiene rubber

    R. V. Sreelekshmi, J. D. Sudha, A. R. Ravindranatha Menon
    Polym. Bull. (2017) 74:783–801

    Phosphorylated cashew nut shell liquid prepolymer (PCNSL) was used as an organomodifier for kaolin and the role of the PCNSL-modified kaolin as a reinforcing nanofiller in natural rubber (NR) and its blends with polybutadiene rubber (BR) was studied. The organomodified kaolin was characterized [...]

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