Research Highlights

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    Emergence of Gold- Mesoporous Silica Hybrid Nanotheranostics : Dox – Encoded, Folate Targeted Chemotherapy with Modulation of SERS Fingerprinting for Apoptosis Toward Tumor Eradication

    Adukkadan N. Ramya, Manu M. Joseph,* Santhi Maniganda, Varsha Karunakaran, Sreelekha T. T.,* and Kaustabh Kumar Maiti* Strategically fabricated theranostic nanocarrier delivery system is an unmet need in personalized medicine. Herein, this study reports a versatile folate receptor (FR) targeted nanoenvelop delivery system (TNEDS) fabricated with gold core silica shell followed by chitosan–folic acid conjugate […]

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    EXPLORATION OF BIOGENIC NANO CHEMOBIOTICS FABRICATED BY SILVER NANOPARTICLE AND GALACTOXYLOGLUCAN WITH AN EFFICIENT BIODISTRIBUTIONIN SOLID TUMOR INVESTIGATED BY SERS FINGERPRINTING

    Manu M. Joseph,Jyothi B. Nair,Ramya N. Adukkadan,NeethuHari,Raveendran K. Pillai,Ananthakrishnan J. Nair,Kaustabh Kumar Maiti,*and Sreelekha Therakathinal T* An incredible exploration ensued of a dual modality nanocomposite whereinchemotherapy in fusion with antibacterial efficacy is obtained in a biogenic fabrication, which transformed as a novel nano-chemobiotics (NCB) prevailing fundamental molecular level investigation by surface-enhanced Raman scattering (SERS) platform. […]

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    SINGLE CELL LIPID PROFILING OF SCENEDESMUS QUADRICAUDA CASA-CC202 UNDER NITROGEN STARVED CONDITION BY SURFACE ENHANCED RAMAN SCATTERING (SERS) FINGERPRINTING

    A.N. Ramya, P.S. Ambily, B.S. Sujitha, MuthuArumugam*, Kaustabh Kumar Maiti* Oleaginous microalgae tend to accumulate neutral lipids as their energy reserve mainly in the form of triacylglycerol (TAG) which can be utilized as the precursor molecule for biodiesel and other nutraceuticalapplication. The TAG level and the fatty acid composition of microalgae modulated by exposing the […]

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    A RATIOMETRIC NEAR INFRARED FLUOROGEN FOR THE REAL TIME VISUALIZATION OF INTRACELLULAR REDOX STATUS DURING APOPTOSIS

    GiridharanSaranya, PalapuravanAnees, Manu M. Joseph, Kaustabh K. Maiti,* and Ayyappanpillai Ajayaghosh* Direct monitoring of apoptotic progression is a major step forward for the early assessment of therapeutic efficacy of certain treatments and the accurate evaluation of the spread of a disease. Here, the regulatory role of glutathione (GSH) is explored as a potential biomarker for […]

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    Antibacterial and anti tubercular evaluation of dihydronaphthalenone-indole hybrid analogues

    Praveen Kumar. V, Renjitha. J, Fathimath Salfeena. C.T, Ashitha. K.T, Sunil Varughese, B. S. Sasidhar* A new series of indole appended dihydronaphthalenone hybrid analogues have been synthesized through the Lewis acid catalyzed Michael addition of indoles to the arylidene/hetero arylidene ketones. All the synthesized derivatives are well characterized through the 1H-NMR, 13C-NMR, HRMS spectroscopic techniques […]

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    Acrylamide formation in plantain (Musa paradisiaca) chips influenced by different ripening stages: A correlation study with respect to reducing sugars, amino acids and phenolic content

    L. Shamla, P. Nisha The effect of ripening on the formation of acrylamide in deep fried plantain chips made from Nendran variety (Musa paradisiaca) was investigated. The precursors of acrylamide formation, reducing sugars (glucose and fructose) and ten major amino acids, were quantified during different stages of ripening using HPLC and correlated with acrylamide formation. […]

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    Green Solid Ionic Liquid Crystalline Electrolyte Membranes with Anisotropic Channels for Efficient Li-Ion Batteries

    Renjith Sasi, Bongu Chandrasekhar, Nallathamby Kalaiselvi*, and Sudha J. Devaki* Adv. Sustainable Syst. 2017, 1600031 A biobased ionic liquid crystal derived solid polymer electrolyte (BILC-SPE) membrane, consisting of polymeric backbone, lithium salt, and cardanol derived ionic liquid crystals along with conventional plasticizer is fabricated using a facile and simple strategy. The in-house prepared solid polymer […]

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    Novel organomodified kaolin/silica hybrid fillers in natural rubber and its blend with polybutadiene rubber

    R. V. Sreelekshmi, J. D. Sudha, A. R. Ravindranatha Menon Polym. Bull. (2017) 74:783–801 Phosphorylated cashew nut shell liquid prepolymer (PCNSL) was used as an organomodifier for kaolin and the role of the PCNSL-modified kaolin as a reinforcing nanofiller in natural rubber (NR) and its blends with polybutadiene rubber (BR) was studied. The organomodified kaolin […]

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    Nanosheets of Organic Molecular Assembly from Aqueous Medium Exhibit High Solidstate Emission and Anisotropic Charge Carrier Mobility

    Samrat Ghosh, Divya Susan Philips, Akinori Saeki and Ayyappanpillai Ajayaghosh, Adv. Mater. 2017, 29, 1605408. Full Text: Link The past 30 years have seen a quantum leap in the field of supramolecular chemistry ‒ a field that was crafted and moulded in the human hands with the inspiration from Mother Nature. Nature has most of […]

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    Studies on natural rubber containing kaolin modified with hexamethylenediamine derivative of phosphorylated cashew nut shell liquid prepolymer

    Sreelekshmi R.V., Brahmakumar M., Sudha J. D., Ravindranatha Menon A. R.* Kaolin was modified with a solution of phosphorylated cashew nut shell liquid prepolymer (PCNSL) containing hexamethylenediamine (HMDA). The organomodified kaolin was characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and infrared spectroscopy (FTIR). Processability characteristics and physico-mechanical properties of natural […]

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