Process for keratinase production demonstrated at tray level using chicken feather and wheat bran as substrates with a yield of 2800 IU/gDS. Codon optimized keratinase gene successfully cloned in Pichia pastoris.
Metabolically engineered Corynebacterium glutamicum strains were successfully made with respect to the production of ?, ?-amino acids (GABA (gamma-aminobutyric acid) and 5-aminovalerate (?-Aminopentanoate) and the sugar acid, D- xylonic acid. The proof of concept with respect to their production from synthetic as well as biomass hydrolysate media is demonstrated.
Demonstrated the use of Cassava Starch Hydrolysate as Sustainable Carbon Source for Exopolysaccharide Production by Lactobacillus plantarum
Two Industrial projects were initiated: (1) the development of a bioprocess for Gibberellic acid (GA3) and (ii) the development of indigenous starter culture consortia for using in dairy products
A bioprocess for the production of 2,3-butanediol from Enterobacter sp. was optimized under lab scale
A biological process for the production of 2,5-Furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfuraldehyde (HMF) using microorganisms was developed with 67% conversion efficiency.
A potential novel plant associated rhizobacteria strain belonging to the novel genus Pokkalii bacter were identified for the first time from Pokkali rice and shown to provide salinity stress alleviation.
Research on the role of stress in oil accumulation by microalgae led to the observation that treatment with stress associated plant hormones significantly increases MUFA and PUFA production by modulation of stress mechanisms and endogenous growth hormone
Selenoprotein gene identified from microalga Scenedesmus quadricauda CASA CC202
Polyhydroxy butyrate production using used cooking oil was demonstrated at lab scale with a yield of 3.8g/L
PANCSIR program on 2G ethanol with participation from 9 CSIR labs and coordinated by NIIST was kick started with a target of reducing the cost of 2G ethanol production to < Rs 100/L. Integrated process scheme is designed and costs worked out for all unit operations. Critical processes and strategies to reduce cost was derived.