Chemical Biology Approach towards Molecular and Nano-carrier drug delivery system (DDS) and diagnostic nano-probe Development
In this area an interdisciplinary team is working at the interface between chemistry, biology and nano science. We are aiming to develop synthetic (peptide, non-peptide, macro cyclic scaffold) and nano-carrier targeted drug-delivery system (TDDS) for the delivery of small molecular drugs, proteins, nucleic acids and plasmid DNAs for combination therapy for both cancer and other non-communicable diseases. Secondly, our interest to develop functionalized nano-particle probes for ultrasensitive detection of various human cancers and other non-communicable disease biomarkers using Raman Scattering (surface enhanced Raman scattering: SERS) and Imaging as a diagnostic modality. Our research effort also focusing on multimodal theranostic nano-probes constructions with SERS, fluorescence, and MRI, as diagnostic modalities and PDT, PTT, chemotherapy as well as immunotherapy for treatment modalities.