Palladiuum catalyzed organic transformations towards the synthesis of novel glycosidase inhibitors as potential pharmaceuticals, design, synthesis and studies of neoglycoconjugates (synthetic carbohydrate Chemistry), development of novel methodologies for the synthesis of cyclooctanoids and related molecules.
Phytopharmaceutical development, New herbal formulations, Analytical method development, Screening of medicinal plants for various ailments, Bioactivity-guided isolation of phytomolecules, Pharmaceutical formulations and Novel Drug Delivery System (NDDS) development….
Targeted Drug Delivery System Development (TDDS), SERS based diagnostic nanoprobe dvelopment, Synthetic modification of bioactive natural products and transformed for targeted delivery, Synthetic methodology
Synthesis of Glycoconjugates of biological significance. Synthesis of Natural Product like small molecule libraries. Structural Elucidation of Natural Products from plants, marine and microbial sources. Design and synthesis of Biosensors as Diagnostic Tools.
The research group focusses on : Pre-formulation of pharmaceuticals, and polymorph/salt/cocrystal/eutectic screening, Solid state properties and phase transition behavior in molecular materials, Crystal engineering and structure-property correlations in functional materials, Mechanical properties in molecular crystals, Open framework materials for gas storage, opto-electronic evaluation and catalysis and Chemical crystallography
Dr. Sasidhar’s group is focused on the interdisciplinary aspects of chemistry with respect to medicinal and material properties. This includes methodology, target-oriented synthesis, medicinal chemistry (Drug-like molecules), Green-chemistry, and phytochemistry. The focused activity of the group on fundamental aspects of organic and medicinal chemistry has led to the successful translational ...