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  • Design and Development of Biogel Through Hierarchical Self‐Organisation of Biomolecule for Sustainable Antibacterial Applications

Design and Development of Biogel Through Hierarchical Self‐Organisation of Biomolecule for Sustainable Antibacterial Applications

This paper describes the design and development of biogel (PPG) through self‐organisation of 3‐ pentadecylphenoxirane grafted polyglucopyranose and demonstration of its antimicrobial applications. 3‐pentadecylphenoxirane (PO) is an epoxy derivative of 3‐pentadecylphenol which is prepared from cashew nut shell liquid, an industrial waste of cashew industry. Polyglucopyranose (PG) is isolated from abundantly available under utlilised jackfruit seed starch. During grafting epoxy converted to hydroxyl group and the grafted molecule is endowed with large number of hydroxyl group, aromatic ring and long hydrocarbon chain which may undergo supramolecular organized structures through various noncovalent interactions such as electrostatic layer by layer assembling (ESLBL), π‐ π and van der Waals to form time dependent columnar and lamellar phases which are confirmed by various microscopic techniques, rheology and XRD. Later demonstrated its antimicrobial screening studies against Gram positive and Gram negative. Results suggests that the developed design strategy can be exploited for generating macroscopically self‐organised biogel systems from small biomolecules for futuristic high performing multifunctional especially antimicrobial applications.

 

Reshma L. Raveendran, Sudha J. Devaki*, Chemistry Select 2018, 3, 3825 – 383 

DOI: 10.1002/slct.201702674