Organic Chemistry : Kumaran A » Professional Experience

HLL Lifecare Ltd (Trivandrum, Kerala, India) – Scientist-E2  – Jun’12- Jun’18 (6 years)

Notable Accomplishments

  • Herbal based product development in health care segment (particularly for reproductive health)
  • Development of herbal based commercial products (e.g. Uterine tonic, Stretch mark cream etc.,)
  • Development an herbal based condom for erectile dysfunction, product for PCOS, etc.
  • Succeeded to receive three research grants from Bill and Melinda Gates Foundation (BMGF) (Total of Rs. 7.8 crore) as Co.P.I.
  • Developed a herbal based product for Bacterial vaginosis in collaboration with an eminent Scientist G.P. Talwar, Talwar Research Foundation, New Delhi

 Sanmar Specialty Chemicals Ltd (Hosur, Tamilnadu, India) – Joint Manager – Aug’09- June’12 (3 years)

Notable Accomplishments

  • Biotransformation/bioconversion of biopharmaceuticals using microbes/enzymes (e.g. conversion of Colchicine to Colchicoside)
  • New product development and Isolation of plant derived drugs in bulk level (Colchicine, Thiocolchicoside, connesine, etc)
  • Semi-synthetic modification and structure elucidation of plant secondary metabolites using NMR, MASS, UV, IR, LC-MS and GC-MS spectroscopic techniques.
  • Supported the production activities, assigned research projects, follow-up and guidance to subordinates

 

National Taiwan University (Graduate Institute of Food Science and Technology, TAIWAN) – Post-Doctoral Fellow – Sep’07-Jul’ 09 (2 years)

Notable Accomplishments

  • Bioassay guided isolation of active compounds for Alzheimer’s disease from Traditional Chinese Medicines
  • Development of new analytical methods for Chinese Medicines and food products using sophisticated chromatographic instruments, like HPLC, GC, LC-MS/MS, etc.
  • Experience with in-vitro assay methodologies and cell culture techniques, (PC12, HepG2, Caco-2 cell lines, etc)
  • Investigation of metabolites of food products after fermentation with GRAS bacteria/yeasts
  • Documenting the research work in the international journals.

Sami Labs Limited (Organica Aromatics Pvt. Ltd) –  (Bangalore, India, an Indian subsidiary of Sabinsa Corporation, New Jersey, USA) – Senior Scientist – Aug’06-Aug’ 07 (1 year)

Notable Accomplishments

  • New product development which leads to flavor and fragrance
  • Isolation and characterization of fragrance constituents from plant sources
  • Synthesis and commercialization of fragrance materials

SPIC Pharmaceuticals Division(R&D Centre, Maraimalai Nagar, Chennai, India) – Senior Research associate –  Apr’96-Jul’03 (7 years)

Notable Accomplishments

  • Successfully developed and standardized 16 herbal formulations for various ailments
  • More than 60 phytochemical markers were isolated, characterized and commercialized
  • Involved in the investigations on the pharmacological and taxonomic applications of secondary metabolites and their role as Anti-HIV, Anti-HBV, Anti-HSV, antifungal agents (about 160 plants, 600 fractions were screened)
  • Development of new analytical methods for herbal drugs and validation of methods using sophisticated liquid chromatographic instruments, like HPLC, GC, HPTLC etc.
  • Semi-synthetic modification and structure elucidation of plant secondary metabolites so as to improve the activity against various ailments
  • Seconded the preparation of SOPs, GMPs and GLPs related documents

  Tamilnadu Dadha Pharmaceuticals Ltd. (Quality Control Department, Chennai, India) –  Quality Control Chemist – May’95-Mar’96 (1 year)  

Notable Accomplishments

  • Conducted chemical and Instrumental analyses of raw materials, in-process samples and finished products
  • Involved in development and validation of analytical methods

Annamalai University (Annamalai Nagar, Tamilnadu, India) – Resource Person – May’94-Apr’95 (1 year)

Notable Accomplishments

Involved in the teaching of theoretical and practical chemistry to M.Sc. Chemistry students