Organic Chemistry : Sasidhar B.S. » Publications


  • Rapid Visual Detection of Amines by Pyrylium Salts for Food Spoilage Taggant.
    Basavaraja D, Dibyendu Dey, Varsha T L, Chettiyan Thodi F. Salfeena, Manas K. Panda, Sasidhar B. Somappa. ACS Appl. Bio Mater. 2020,
  • I2/TBHP Mediated Diastereoselective Synthesis of Spiroaziridines.
    Kizhakkan Thiruthi Ashitha, Puthiya  Purayil Vinaya, Ajay Krishna, Deepthy Cheeran Vincent, Renjitha Jalaja, Sunil Varughese, Sasidhar Balappa Somappa. Org. Biomol. Chem., 2020,
  • Immobilizing biogenically synthesized palladium nanoparticles on cellulose support as a green and sustainable dip catalyst for cross-coupling reaction. Manjunatha Kempasiddaiah, Vishal Kandathil, Ramesh B. Dateer, S. Sasidhar, Shivaputra A. Patil, Siddappa A. Patil. Cellulose, 2020,
  • DNA as a Bioligand Supported on Magnetite for Grafting Palladium Nanoparticles for Cross-Coupling Reaction. Vishal Kandathil, Manjunatha Kempasiddaiah, Sanna Kotrappanavar Nataraj, Sasidhar Balappa Somappa, Siddappa A. Patil. Appl Organometal Chem. 2020,
  • Immobilized N-heterocyclic carbene-palladium(II) complex on graphene oxide as efficient and recyclable catalyst for Suzuki–Miyaura cross-coupling and reduction of nitroarenes. Vishal Kandathil, Bhakti Kulkarni, Aisha Siddiqa, Manjunatha Kempasiddaiah, S. Sasidhar, Shivaputra A. Patil, Siddappa A. Patil. Catalysis Letters, 2020, 150:384-403.


  • Magnetite tethered mesoionic carbene?palladium (II): Anefficient and reusable nanomagnetic catalyst for Suzuki?Miyaura and Mizoroki?Heck cross?coupling reactions inaqueous medium. Manjunatha Kempasiddhaiah, Vishal Kandathil, Ramesh B. Dateer, Balappa Sasidhar, Shivaputra A. Patil, Siddappa A. Patil. Appl Organometal Chem. 2019, e4846.
  • From Agriculture Residue to Catalyst Support; A Green and Sustainable Cellulose-Based Dip Catalyst for C-C Coupling and Direct Arylation. Vishal Kandathil, Manjunatha Kempasiddaiah, Sasidhar B. S., Siddappa A. Patil. Carbohydrate Polymers. 2019, 223, 115060.


  • Synthesis of symmetrical and unsymmetrical triarylpyrylium ions by inverse electron demand Diels-Alder reaction.  C. T. Fathimath Salfeena, Basavaraja, K. T. Ashitha, V. Praveen Kumar, Sunil Varughese, Cherumuttathu H. Suresh and  B. S. Sasidhar. Chemical Communications, 2018, 54, 12463-12466.
  • Synthesis of 1,2,4-Trisubstituted-(1H)–Imidazoles Through Cu(OTf)2/I2 Catalyzed C-C Bond Cleavage of Chalcones and Benzylamines. Fathimath Salfeena, Chettiyan Thodi; Jalaja, Renjitha; Davis, Rincy; Suresh, Eringathodi; Somappa Sasidhar. ACS Omega, 2018, 3 (7), 8074–8082
  • Discovery of Natural Product Derived Labdane Appended Triazoles as Potent Pancreatic Lipase Inhibitors.  Renjitha Jalaja, Shyni Gangadharan Leela, Praveen Kumar Valmiki, Chettiyan Thodi F Salfeena, Kizhakkan T Ashitha, Venkata Rao D Krishna Rao, Mangalam S Nair, Raghu Kozhiparambil Gopalan, and Sasidhar Balappa Somappa. ACS Med. Chem. Lett., 2018, 9 (7), 662–666.
  • Phytochemical composition of Caesalpinia crista extract as potential source for inhibiting cholinesterase and ?-amyloid aggregation: Significance to Alzheimer’s disease. Kolambe Rajappa Chethana, Balappa Somappa Sasidhar, Mahadeva Naika,  Rangappa Sangappa Keri. Asian Pacific Journal of Tropical Biomedicine, 2018, 8(10), 500-512.
  • Biological evaluation of indole appended triazolothiadiazepine conjugates as potent anticancer agents. Kizhakkan T. Ashitha , Chettiyan T.F. Salfeena, Jalaja Renjitha, Valmiki P. Kumar, Rajesab Parveen, Balappa S. Sasidhar. Current Bioactive Compounds, 2018, 14 (4), 445-450.
  • Functionalized Pyrimidines from Alkynes and Nitriles: Application towards the Synthesis of Marine Natural Product Meridianin Analogs.  Banyangala Mohan, Chettiyan Thodi F. Salfeena, Kizhakkan T. Ashitha, Gopika V. Krishnan, Abdul Rasheed S. Jesmina, Angela M. Varghese, Siddappa A. Patil, Bhaskaran Nair S. Dileep Kumar, Balappa S. Sasidhar.  ChemistrySelect2018, 3, 6394 – 6398.
  • Green synthesis of palladium nanoparticles: Applications in aryl halide cyanation and Hiyama cross-coupling reaction under ligand free conditions.  Vishal Kandathil, Ramesh B. Dateer, B. S. Sasidhar, S. A. Patil, Siddappa A. Patil. Catalysis Letters, 2018, 148, 1562–1578.
  • Magnetic nanoparticle tethered Schiff base-palladium(II): highly active and reusable heterogeneous catalyst for Suzuki-Miyaura cross-coupling and reduction of nitroarenes in aqueous medium at room temperature.   K. Manjunatha, Tuhin S. Kole, Vishal Kandathil, Ramesh B. Dateer, Geetha Balakrishna, B. S. Sasidhar,  Shivaputra A. Patil, Siddappa A. Patil.   Appl Organometal Chem. 2018, 32, e4266.
  • An Uncommon Multicomponent Reaction Involving Nucleophilic Heterocyclic carbenes: Facile Synthesis of Fully Substituted Cyclopentanones.   Nair, Vijay; Krishnan, Jagadeesh; Jose, Anu; S, Sasidhar; Suresh, Eringathodi; S. Menon, Rajeev.  Organic Chemistry Frontiers, 2018, 5, 1202-1208.
  • A new magnetically recyclable heterogeneous palladium(II) as a green catalyst for Suzuki-Miyaura cross-coupling and reduction of nitroarenes in aqueous medium at room temperature.   Vishal Kandathil, Tuhin S. Koley, K. Manjunatha, Ramesh B. Dateer, Rangappa S. Keri,   B. S. Sasidhar, Shivaputra A. Patil, Siddappa A. Patil.   Inorganica Chimica Acta, 478 (2018) 195–210


  • BF3•OEt2 Mediated Tandem Annulation: A Strategy to Construct Functionalized Chromeno-, and Pyrano- Fused Pyridines. Ashitha K. T,  Praveen Kumar V,  Fathimath Salfeena C. T,  B. S. SasidharJournal of Organic Chemistry, 2018, 83, 113-124.
  • Epoxyazadiradione purified from the Azadirachtaindica seed induced mitochondrial apoptosis and inhibition of NF-B nuclear translocation in human cervical cancer cells. Shilpa G., Renjitha J., Saranga R., Sajin Francis K., Mangalam S. Nair, Beena Joy, B. S. Sasidhar and Priya S. Phytotherapy Research, 2017, 31, 1892–1902.
  • An overview of benzo [b] thiophene based medicinal chemistry. Rangappa S. Keri, Karam Chand, Srinivasa Budagumpi, B. S. Sasidhar, Siddappa A. Patil and Bhari Mallanna Nagaraj. European Journal of Medicinal Chemistry, 2017, 138, 1002-1033.
  • Biological evaluation of indole appended triazolothiadiazepine conjugates as potent anticancer agents. Kizhakkan T. Ashitha, C.T. Fathimath. Salfeena, Jalaja Renjitha, Valmiki P. Kumar, Rajesab Parveen and B. S. Sasidhar. Current Bioactive Compounds, 2017, DOI: 10.2174/1573407213666170707150757.
  • A Convenient, Efficient and Reusable N-Heterocyclic Carbene-Palladium(II) Based Catalyst Supported on Magnetite for Suzuki–Miyaura and Mizoroki–Heck Cross-Coupling Reactions. Siddappa A Patil, Vishal Kandathil, Bradley Fahlman, B. S. Sasidhar and S. Patil. New Journal of Chemistry, 2017, 41, 9531-9545.
  • Antibacterial and anti-tubercular evaluation of Dihydronaphthalenone-indole hybrid analogues. Praveen Kumar. V, Fathimath Salfeena. C.T, Ashitha. K.T, Sunil Varughese and B. S. Sasidhar. Chem Biol Drug Des, 2017, 90, 703-708.
  • Novel NHC-mediated synthesis of pyrrolo[2,1-a]isoquinolines and their photophysical investigations. Vijay Nair, Jagadeesh Krishnan, BalaramanVedhanarayanan, B. S. Sasidhar and Sunil Varughese. Chemistry-An Asian Journal, 2017, 12(6), 623–627.
  • Magnetic Nanoparticle-Supported N-Heterocyclic Carbene-Palladium (II): A Convenient, Efficient and Recyclable Catalyst for Suzuki-Miyaura Cross-Coupling Reactions. Vishal K, Bradley D. Fahlman, B. S. Sasidhar, S. A. Patil and Siddappa A. Patil. Catalysis Letters, 2017, 147,900–918.



  • BF3•Et2O mediated one-step synthesis of N-substituted-1,2-dihydropyridines, indenopyridines and 5,6-dihydroisoquinolines. C. T. Fathimath Salfeena, K. T. Ashithaa, and B. S. Sasidhar. Organic & Biomolecular Chemistry, 2016, 14, 10165-10169.
  • Sequential NHC-Catalyzed Reaction of Enals and Cyclic Aryldiene-1,3-Diones: Synthesis of Tricyclic Chromenones and Related Compounds. Jagadeesh Krishnan, Sneha Mathew, P. Anjana Jayaprakash, B. S. Sasidhar, T. S. Mayadevi, E. Suresh and Vijay Nair. Asian Journal of Organic Chemistry, 2016, 5(12), 1447–1451.
  • Synthesis of novel Indolylbenzo[b][1,4] diazepins as a potent antimicrobial and antioxidant agents. J. S. Biradar and B. S. Sasidhar. Arabian J Chem, 2016, 9, S1063–S1068.


  • Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents. Rangappa S. Keri, Siddappa A. Patil and B. S. Sasidhar. European Journal of Medicinal Chemistry, 2015, 100, 257-269.
  • Lewis Acid Catalyzed C-3 Alkylidene cyclopentenylation of Indoles: An Easy Access to Functionalized Indoles and Bisindoles. Sarath Chand S., B. S. Sasidhar, Praveen Prakash, Sasikumar P., Preethanuj P., Florian Jaroschik, Dominique Harakat, Jean-Luc Vasse and Radhakrishnan K. V. RSC advances, 2015, 5, 38075.
  • One-pot synthesis of indole appended heterocycles as potent anti-inflammatory, analgesic, and CNS depressant agents. B. S. Sasidhar, Jaiprakash SharnappaBiradar, ParveenRajesab, Shaik Rahber and MetySundar. Monatshefte fur Chemie, 2015, 146(12),2067–2078.


  • Trapping the Lewis acid generated transient species from pentafulvene derived diazanorbornenes with ortho functionalized aryl iodides and aliphatic alcohols. S. Sarath Chand, S. Saranya, P. Preethanuj, B. P. Dhanya, E. Jijy, Praveen Prakash, B. S. Sasidhar, Jan Szymoniak, P. V. Santhini, and K. V. Radhakrishnan. Organic & Biomolecular Chemistry, 2014, 12(19), 3045-61.
  • Design and synthesis of novel thiopheno-4-thiazolidinylindoles as potent antioxidant and antimicrobial agents. Jaiprakash. S. Biradar, Rajesab Parveen and B. S. Sasidhar. Chemical Papers, 2014, 68 (3), 392–400.
  • Microwave assisted Synthesis of Novel Imidazolopyridinyl indoles as Potent Antioxidant and Antimicrobial Agents. Jaiprakash S. Biradar, Parveen Rajesab, and B. S. Sasidhar. Journal of Chemistry, 2014,


  • A Mini Library of Novel Indolyl triazolo thiadiazepines: Synthesis, Antioxidant and Antimicrobial Evaluations. Jaiprakash. S. Biradar, Rajesab Parveen, Naveen B. and B. S. Sasidhar. The Scientific World Journal, 2013,
  • Synthesis of some bisindolyl analogs for in vitro cytotoxic and DNA cleavage studies. B. S. Sasidhar and J. S. Biradar. Med Chem Res, 2013, 22, 3518–3526.

2012- 2008

  • Solvent-free, microwave assisted Knoevenagel condensation of novel 2,5-disubstituted indole analogues and their biological evaluation. J. S. Biradar and B. S. Sasidhar. Eur J Med Chem, 2011, 46, 6112-6118.
  • Synthesis, antioxidant and DNA cleavage activities of novel indole derivatives. J. S. Biradar, B. S. Sasidhar and R. Parveen. Eur J Med Chem, 2010, 45, 4074-4078.
  • Synthesis of new indolylbenzodiazepins and their DNA cleavage and antimicrobial activities. J. S. Biradar, R. Parveen, B. S. Sasidhar and S. M. Praveen. Ind J Het Chem, 2010, 20, 181-182.
  • A versatile one-pot synthesis of novel substituted pyrazoles, isaxazoles and their antimicrobial activity. J. S. Biradar, B. S. Sasidhar, S. M. Praveen and B. Sharanbasappa. Organic Chemistry, 2009, 5(3), 262-265.
  • Improved synthesis of some pyrazolines under microwave. J. S. Biradar, Praveen. S. Mugali, B. Sharanabasappa and B. S. Sasidhar. Ind J Het Chem, 2008, 18, 141-144.
  • One pot synthesis of substituted imidazoles containing indole and their antimicrobial activities. Jaiprakash. S. Biradar, Praveen. S. Mugali, B. S. Sasidhar and Parveen. Rajesab. Organic Chemistry, 2008, 4(6-8), 408-411.
  • Synthesis ofnovel 2, 5-disubstituted-3[3’-(pyridine-2”-yl)-1’-substituted pyrazole-5’-yl and isoxazol-5’-yl]-1H-indole in triethyl amine medium. J. S. Biradar, B. Sharanbasappa, S. M. Praveen and B. S. Sasidhar. Organic Chemistry, 2008, 4(4), 266-268.