Seminars

  • Environmental impact of synthetic Nano-materials

    Dr. Krishnakumar B.,   

    Nano materials are increasingly being used in large number of consumer products. However, at least part of these materials ultimately reaches the natural environment mainly during waste disposal. In the natural environment how these synthetic materials affecting the various life forms upon which the very existence of our plant rely on. In the present discussion, the effect of different nano materials on various microbial communities will be addressed.Nano materials are increasingly being used in large number of consumer products. However, at least part of these materials ultimately reaches the natural environment mainly during waste disposal. In the natural environment how these synthetic materials affecting the various life forms upon which the very existence of our plant rely on. In the present discussion, the effect of different nano materials on various microbial communities will be addressed.



    On 18th September 2012 at 11:30 am
  • An Overview of new Drug targets in Mycobacterium tuberculosis

    Dr. K. Madhavan Nampoothiri,   

    The recent past has experienced a renaissance in tuberculosis (TB) research. TB research has got a new dimension and momentum due to many of the newly developed molecular biology methods and genetic tools and now the whole genome sequences of Mycobacterium tuberculosis strains are also available. An increase in the prevalence of drug resistant strains of M. tuberculosis has renewed focus on the development of new drugs against this millennia old disease. The identification of new targets in M. tuberculosis that might be inhibited to effectively kill the existing strains is now a global pursuit. The present talk will summarize the current status of TB, pathogenecity , current treatment and need to go for new targets and the recently identified drug targets in M. tuberculosis that have been validated beyond initial genetic identification. Advancing these defined targets for the development of inhibitors has the potential to produce new drugs with novel mechanisms of actions and benefit TB patients worldwide.



    On 17th August 2012 at 11:30 am
  • Sweet drugs and Materials: New horizons in carbohydrate chemistry

    Dr. K.V. Radhakrishnan,   

    Carbohydrates have unique roles to play within living systems and actively control a whole range of biological processes including cell growth and differentiation. As well as providing solutions to some unanswered scientific questions, a study of carbohydrates may even offer novel opportunities for therapeutic treatments of diseases which are difficult to treat. Therefore design and synthesis of novel carbohydrate based multivalent ligands capable of mimicking biological processes has gained much attention. The knowledge that these multivalent ligands can effectively interact with biological molecules like lectins, DNA etc. made the carbohydrate chemists to devote themselves into this area. The magnitude of interaction of these multivalent ligands is ten and hundred fold excess when compared to the monovalent counter parts. Apart from these biological applications, carbohydrate based ligands have found to be excellent candidates for studying some material applications also. Numerous carbohydrate based liquid crystalline materials and surfactants have been synthesized. Aggregation of sugar conjugated molecules into vesicles and nanorods have also been investigated. The presentation will give an overview of the role of carbohydrates in cell recognition and its application in medicinal chemistry. The role of carbohydrates in the self assembly of various synthetic materials will also be discussed.



    On 9th July 2012 at 2:00 pm
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