Microbial Processes and Technology - Highlights
Highlights
- Process for keratinase production demonstrated at tray level using chicken feather and wheat bran as substrates with a yield of 2800 IU/gDS.
Polyunsaturated Fatty Acids (PUFA) and Nutraceuticals from Algae
Photosynthetic organisms are the primary producers of PUFA and the major producers of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) are algae. These PUFAs are essential in the metabolism of animals as they are implicated as the starting material for synthesis of several signalling molecules. The dietary content of such fatty acids are therefore important in both humans and other animals.
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Metabolic engineering of Pichia pastoris for enhanced flux towards Squalene production
The linear polyunsaturated triterpene squalene, exists in all organisms and has immense applications in food, pharmaceutical and cosmetic industries. New applications of squalene as an enhancer are ever increasing ensuing in its growing demand. Development of a Pichia model with accelerated Farnesyl diphosphate (FPP) precursor flux towards squalene and reduced squalene drain towards ergosterol is being studied. Lipid droplets provide extra space for accumulation of squalene in cytoplasm.
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Membrane Biophysics, Membrane biology and Synthetic Biology
Understanding transport across membranes has tremendous implications in understanding how organisms/cells react to its environment. This includes the elucidation of metabolic circuits, antibiotic resistance, development of membrane potential and hence biological generation of energy and much more. Studies on synthetic membrane vesicles at MPTD is focused on understanding the transport phenomena, and also on creating functional artificial cells that mimic microorganisms
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Corynebactin, a Cyclic Catecholate Siderophore from Corynebacterium glutamicum ATCC 14067 (Brevibacterium sp. DSM 20411)
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Crystal structure of pimolin, C26H20O8
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Candida rugosa lipases: Molecular biology and versatility in biotechnology
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Organosolvent pretreatment and enzymatic hydrolysis of rice straw for the production of bioethanol
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Potential plant growth-promoting activity of Serratia nematodiphila NII-0928 on black pepper (Piper nigrum L.)
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Production of a highly glucose tolerant beta-glucosidase by Paecilomyces variotii MG3: optimization of fermentation conditions using Plackett-Burman and Box-Behnken experimental designs
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